The trip from Hyannis to Las Vegas is best accomplished by flying from Boston Logan to Harry Reid International Airport. The distance is approximately 4,100 kilometers. You will cross the central United States, often flying over the Midwest and the Rockies. Las Vegas is located in the Mojave Desert. This route takes you from the coastal charm of Cape Cod to the neon lights of the Strip.
Total Distance: 4,500 km driving, 4,100 km air distance.
Southwest Airlines often offers competitive rates with two free checked bags.
March to May or September to November to avoid extreme desert heat.