The drive from Indianola to San Francisco covers 1,800 miles. You will take I-80 West all the way through Nebraska, Wyoming, Utah, and Nevada. The drive takes approximately 28 hours. This is a classic cross-country route. It is a scenic journey through the mountains and the Sierra Nevada.
Total Distance: 2900 km driving distance, 2600 km air distance.
Plan for multiple overnight stops.
September to October for clear weather.