The trip from Jefferson to Charleston is a 300-mile journey to the coast. Driving is the most practical mode, taking about 4 hours and 30 minutes via I-20 East and I-26 East. You will pass through Columbia before heading toward the Atlantic. Charleston is famous for its historic architecture, cobblestone streets, and world-class dining. Expect heavy traffic as you approach the city.
Total Distance: 483 km driving, 400 km air distance.
I-26 can be very busy near Charleston.
Spring or Autumn for mild coastal weather.