Driving
Key Largo to Memphis
Updated: 28 May 2026
The distance from Key Largo to Memphis is approximately 1,600 kilometers. The most practical way to travel is to drive via I-75 and I-22. The drive typically takes 16 to 17 hours. Memphis is a major city known for its music scene, particularly blues and rock and roll.
Total Distance: 1,600 km driving distance; 1,400 km straight-line air distance.
Fastest Way
Driving is the most practical way to travel this distance.
Cheapest Way
Driving your own vehicle is the most cost-effective method.
Compare Key Largo to Memphis Routes
Driving
Direct
Duration
16 hours 30 mins
Avg Price
$175-$225 in fuel
Operator
Personal Vehicle
Route
US-1 North to Florida Turnpike to I-75 North to I-22 West
This is a long drive; plan for overnight stops if necessary.
Travel Tips
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Toll RoadsThe Florida Turnpike has many tolls; use a SunPass.
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TrafficMemphis traffic can be heavy; avoid rush hour.
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ParkingDowntown Memphis has several public parking garages.
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Sun ProtectionEven in Tennessee, wear sunscreen during the summer.
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HydrationStay hydrated while traveling.
Safety Tips
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Road SafetyStay alert for heavy traffic on I-75 and I-22.
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WeatherBe prepared for changing weather conditions as you travel north.
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EmergencyKeep your phone charged and have a list of emergency contacts.
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Vehicle MaintenanceCheck your car's condition before starting the long drive.
People Also Ask
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How long is the drive to Memphis?The drive takes about 16 to 17 hours.
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Are there tolls?Yes, the Florida Turnpike is a toll road.
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Is it better to fly or drive?Driving is more flexible, while flying is faster.
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What is the best time to visit?Spring and fall are ideal.
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Can I take a train?There is no direct train service from Key Largo to Memphis.
Quick Info
- From Key Largo, Florida, United States
- To Memphis, Tennessee, United States
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Modes
Best Time to Travel
Spring and fall for pleasant weather.
Things to Do in Memphis
1
Graceland
Visit the home of Elvis Presley, one of the most famous music landmarks in the world.
2
Sun Studio
Tour the studio where rock and roll was born.
3
Beale Street
Enjoy the live music and nightlife on this famous street.
4
National Civil Rights Museum
Explore the history of the civil rights movement at this historic site.
Tags
Key Largo to Memphis
driving to Memphis
I-75 to I-22 route
Memphis travel guide
Key Largo to Memphis distance
long-distance travel
Florida to Tennessee
travel planning
