Key Largo
Key Largo
Driving

Key Largo to Memphis

Updated: 28 May 2026

The distance from Key Largo to Memphis is approximately 1,600 kilometers. The most practical way to travel is to drive via I-75 and I-22. The drive typically takes 16 to 17 hours. Memphis is a major city known for its music scene, particularly blues and rock and roll.

Total Distance: 1,600 km driving distance; 1,400 km straight-line air distance.
Fastest Way
Driving is the most practical way to travel this distance.
Cheapest Way
Driving your own vehicle is the most cost-effective method.
Compare Key Largo to Memphis Routes
Driving
Direct
Duration
16 hours 30 mins
Avg Price
$175-$225 in fuel
Operator
Personal Vehicle
Route
US-1 North to Florida Turnpike to I-75 North to I-22 West

This is a long drive; plan for overnight stops if necessary.

Travel Tips
  • Toll Roads
    The Florida Turnpike has many tolls; use a SunPass.
  • Traffic
    Memphis traffic can be heavy; avoid rush hour.
  • Parking
    Downtown Memphis has several public parking garages.
  • Sun Protection
    Even in Tennessee, wear sunscreen during the summer.
  • Hydration
    Stay hydrated while traveling.
Safety Tips
  • Road Safety
    Stay alert for heavy traffic on I-75 and I-22.
  • Weather
    Be prepared for changing weather conditions as you travel north.
  • Emergency
    Keep your phone charged and have a list of emergency contacts.
  • Vehicle Maintenance
    Check your car's condition before starting the long drive.
People Also Ask
  • How long is the drive to Memphis?
    The drive takes about 16 to 17 hours.
  • Are there tolls?
    Yes, the Florida Turnpike is a toll road.
  • Is it better to fly or drive?
    Driving is more flexible, while flying is faster.
  • What is the best time to visit?
    Spring and fall are ideal.
  • Can I take a train?
    There is no direct train service from Key Largo to Memphis.
Quick Info
  • From Key Largo, Florida, United States
  • To Memphis, Tennessee, United States
  • Modes
Best Time to Travel

Spring and fall for pleasant weather.

Things to Do in Memphis
1
Graceland
Visit the home of Elvis Presley, one of the most famous music landmarks in the world.
2
Sun Studio
Tour the studio where rock and roll was born.
3
Beale Street
Enjoy the live music and nightlife on this famous street.
4
National Civil Rights Museum
Explore the history of the civil rights movement at this historic site.
Tags
Key Largo to Memphis driving to Memphis I-75 to I-22 route Memphis travel guide Key Largo to Memphis distance long-distance travel Florida to Tennessee travel planning