The distance from Key Largo to New Orleans is approximately 1,300 kilometers. The most practical way to travel is to drive via I-10. The drive typically takes 13 to 14 hours. New Orleans is a major city known for its unique culture, music, and food.
Total Distance: 1,300 km driving distance; 1,100 km straight-line air distance.
This is a long drive; plan for overnight stops if necessary.
Spring and fall for pleasant weather.