How long is the flight to San Francisco?

The flight time is about 6 hours.

Is it better to fly or drive?

Flying is much faster and more practical.

Are there direct flights?

Yes, there are many direct flights from Miami to San Francisco.

There is no direct train service from Key Largo to San Francisco.

Key Largo

San Francisco

Flight

Key Largo to San Francisco

Updated: 28 May 2026

The distance from Key Largo to San Francisco is approximately 4,500 kilometers. The most practical way to travel is to drive to Miami International Airport and take a flight to San Francisco International Airport (SFO). Driving is possible but takes over 42 hours. San Francisco is a major city known for its iconic bridge, hills, and vibrant culture.

Total Distance: 4,500 km driving distance; 4,100 km straight-line air distance.

Fastest Way

Flying is the only practical way to travel this distance in a reasonable time.

Cheapest Way

Flying from Miami is the most cost-effective and time-efficient method.

Compare Key Largo to San Francisco Routes

Flight

Direct

Duration

6 hours (flight time)

Avg Price

$300-$600

Operator

United Airlines

Route

MIA to SFO

Book your flight in advance for the best prices.

Travel Tips

Airport Transport
Use the BART train or ride-sharing to get to the airport in Miami.
Packing
Pack for the weather in San Francisco, which can be very different from Florida.
Navigation
Use the cable cars or ride-sharing to navigate San Francisco easily.
Sun Protection
Even in San Francisco, wear sunscreen during the summer.
Hydration
Stay hydrated while traveling.