The drive from Keystone to St. Louis is approximately 1,400 kilometers. You will head east on I-90 before turning south and east on I-70. This route takes you through the heart of the Midwest. Expect a travel time of about 14 hours. It is a long but straightforward drive.
Total Distance: 1,400 km driving, 1,200 km air distance.
Stop in Kansas City for a break.
May to September for mild weather and outdoor activities.