Traveling from Lake George to Buffalo involves a 280-mile trek across the heart of New York State. The most direct route is via I-87 S to I-90 W, traversing the entire length of the New York State Thruway. You will pass through major cities like Utica and Syracuse before arriving in Western New York. The drive typically takes 4.5 hours under normal traffic conditions.
Total Distance: 450 km driving distance; 380 km straight-line air distance.
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Connecting
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Direct
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| Duration | 7 hours | 4 hours 30 mins |
| Avg Price | 80-120 USD | 50-70 USD |
| Operator | Greyhound | Personal Vehicle |
| Route | Bus from Glens Falls to Albany, then transfer to Buffalo. | I-87 S to I-90 W. |
| Tip | Book tickets in advance for lower fares. | Avoid rush hour in Syracuse to save time. |
Late spring or early autumn for comfortable driving temperatures.