Flight
Driving
Lake Mary to Key West
Updated: 28 May 2026
The journey from Lake Mary to Key West covers approximately 650 kilometers. Driving is a scenic experience, taking about 7-8 hours via the Florida Turnpike and US-1. You can also fly from Orlando to Key West International Airport (EYW). Key West is famous for its laid-back atmosphere, historic sites, and beautiful sunsets. Plan your drive to enjoy the Overseas Highway.
Total Distance: 650 km driving, 550 km air distance.
Fastest Way
Flight, taking approximately 1.5 hours.
Cheapest Way
Driving, especially if you have multiple passengers.
Compare Lake Mary to Key West Routes
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Direct
|
Direct
|
|
|---|---|---|
| Duration | 1 hour 30 mins | 7 hours 30 mins |
| Avg Price | $200 - $500 | $100 - $150 in fuel |
| Operator | Silver Airways | Personal Vehicle |
| Route | MCO to EYW | Florida Turnpike to US-1 |
| Tip | Book early to get the best rates. | The drive through the Keys is beautiful; take your time. |
Travel Tips
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TrafficExpect traffic on US-1, especially on weekends.
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ParkingParking in Key West is limited; use public garages.
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DiningTry the local key lime pie at restaurants.
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NavigationUse GPS to navigate the island.
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PackingBring sunscreen, sunglasses, and comfortable clothing.
Safety Tips
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Road SafetyBe cautious on the narrow sections of the Overseas Highway.
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Sun SafetyUse high-SPF sunscreen to protect against the strong sun.
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Emergency PrepKeep a supply of water and snacks in your car.
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Water SafetyBe cautious of strong currents when swimming.
People Also Ask
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Is there a direct flight?Yes, there are direct flights from MCO to EYW.
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How long is the drive?It takes about 7-8 hours of driving time.
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What is the best route?US-1 is the only road to Key West.
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Are there tolls?Yes, expect tolls on the Florida Turnpike.
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Is Key West safe?Yes, tourist areas are generally safe.
Quick Info
- From Lake Mary, Florida, United States
- To Key West, Florida, United States
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Modes
Best Time to Travel
March to May for pleasant weather.
Things to Do in Key West
1
Duval Street
Experience the vibrant nightlife, shops, and restaurants in the heart of Key West.
2
Ernest Hemingway Home
Tour the historic home of the famous author and see the six-toed cats.
3
Mallory Square
Watch the famous sunset celebration with street performers and local vendors.
4
Dry Tortugas National Park
Take a ferry or seaplane to this remote park for snorkeling and history.
Tags
Lake Mary to Key West
driving to Key West
flights to Key West
US-1
Key West travel guide
Florida road trip
cheapest travel to Key West
traveling to the Keys
