Is there a direct train?

No, there is no direct Amtrak service from St. Louis to New Orleans.

How long is the drive?

The drive is approximately 11 hours without traffic.

What is the best airport?

Louis Armstrong New Orleans International Airport (MSY) is the primary hub.

There are minimal tolls on this route depending on your specific path through Memphis.

Is it safe to drive alone?

Yes, the I-55 corridor is a well-traveled interstate route.

Lake St. Louis

New Orleans

Flight Driving

Lake St. Louis to New Orleans

Updated: 28 May 2026

The journey from Lake St Louis to New Orleans covers approximately 1,100 kilometers via the I-55 South corridor. Driving takes roughly 11 hours, passing through Memphis and Jackson. Alternatively, you can fly from St. Louis Lambert International Airport to Louis Armstrong New Orleans International Airport. The flight duration is about 2 hours, though total travel time including security is 4 hours. This route transitions from the Midwest plains to the humid, culturally rich Mississippi Delta.

Total Distance: 1,100 km driving, 950 km air distance.

Fastest Way

Flight is the fastest, taking 4 hours total including airport transit.

Cheapest Way

Driving is the cheapest option at approximately $180 for fuel for a single traveler.

Compare Lake St. Louis to New Orleans Routes

	Flight Connecting	Driving Direct
Duration	4 hours	11 hours
Avg Price	$250-$450	$150-$200 in fuel
Operator	Southwest Airlines	Personal Vehicle
Route	STL to MSY via BNA or DAL.	I-70 E to I-255 S to I-55 S through Memphis and Jackson.
Tip	Book at least three weeks in advance for lower fares.	Stop in Memphis for authentic barbecue at Central BBQ.

Travel Tips

Parking
Parking in the French Quarter is expensive; use hotel garages.
Hydration
New Orleans is humid; carry water at all times.
Footwear
Wear comfortable walking shoes for uneven historic sidewalks.
Dining
Make dinner reservations for popular restaurants like Commander's Palace.
Transport
Use the LePass app for streetcar and bus tickets.