The drive from Lake Worth Beach to Jacksonville is a 300-mile journey north along the Atlantic coast. You will primarily use I-95 North, which runs the entire length of the state. The trip takes approximately 4.5 to 5 hours, depending on traffic in the major metropolitan areas you pass through. Jacksonville is the largest city by area in the contiguous United States and offers a different pace of life than South Florida.
Total Distance: 480 km driving distance; 430 km straight-line air distance.
I-95 is a straight shot, but watch for construction near Daytona Beach.
Spring or fall for mild weather and outdoor activities.