The drive from Laramie to San Francisco is a 1,000-mile journey across the high desert of Wyoming, the mountains of Nevada, and the Sierra Nevada range. Driving via I-80 West is the most direct route, taking approximately 16 hours. You will pass through the scenic Great Basin and the Sierra Nevada mountains. This route is popular for those traveling to the Bay Area.
Total Distance: 1,650 km driving distance; 1,350 km straight-line air distance.
Be prepared for long stretches of desert driving.
September to October for mild weather in San Francisco.