The drive from Lawton to Chicago is approximately 900 miles and takes about 14 hours. You will travel northeast through Oklahoma, Missouri, and Illinois, primarily using I-44 and I-55. This is a long but straightforward drive through the Midwest. Be prepared for changing weather conditions and heavy traffic in the metro areas.
Total Distance: Driving distance 1,450 km, straight-line air distance 1,250 km.
Expect heavy traffic in the St. Louis and Chicago areas.
Spring and fall are the most comfortable times for this drive.