Is there a train to Buffalo?

Yes, Amtrak stops at the Buffalo-Depew station.

How much are the tolls?

Expect to pay around $25-$30 in tolls for this trip.

The downtown area is walkable, but you will need a car for the suburbs.

What is the best route?

I-90 West is the most direct and reliable route.

Yes, there are many hotels near the downtown area and the airport.

Lee

Buffalo

Driving

Lee to Buffalo

Updated: 28 May 2026

The drive from Lee to Buffalo covers 480 kilometers, following I-90 West across the entire state of New York. This journey takes approximately 5 hours. You will pass through the Mohawk Valley, Syracuse, Rochester, and finally reach Buffalo on the shores of Lake Erie. It is a long but straightforward highway drive.

Total Distance: 480 km driving distance; 410 km straight-line air distance.

Fastest Way

Driving via I-90 is the fastest route, taking 5 hours.

Cheapest Way

Driving is the most practical and cost-effective method, costing about $80 in fuel.

Compare Lee to Buffalo Routes

Driving

Direct

Duration

5 hours

Avg Price

$70 - $95 in fuel

Operator

Personal Vehicle

Route

I-90 West (Mass Pike to NY Thruway) to Exit 51.

Buffalo is famous for its chicken wings and proximity to Niagara Falls.

Travel Tips

Tolls
The NY Thruway is a toll road; ensure your E-ZPass is active.
Traffic
Buffalo traffic is generally manageable, but avoid rush hour on I-190.
Weather
Buffalo can be very cold and snowy in winter; check road conditions.
Dining
Try the original Buffalo wings at a local restaurant.
Parking
Downtown Buffalo has several parking garages and street parking.

Safety Tips

Speeding
State police are active on the Thruway; maintain a steady speed.
Visibility
Use your headlights during the frequent lake-effect snow squalls.
Emergency
Keep a winter emergency kit in your trunk during the colder months.
Fatigue
Take a break at the service plazas if you feel tired during the 5-hour drive.