The trip from Lee to Portland spans 320 kilometers across Massachusetts and New Hampshire into Maine. The most direct route involves taking I-90 East to I-495 North, then connecting to I-95 North. Expect a travel time of approximately 4 hours depending on traffic near Boston. This route takes you through the heart of New England, passing near major urban centers before reaching the coast. Driving is the most practical mode of transport for this distance.
Total Distance: 320 km driving, 260 km air distance.
Be prepared for tolls on the Massachusetts Turnpike and the Maine Turnpike.
June to August for coastal weather or October for foliage.