The journey from Lee's Summit to Memphis covers approximately 450 miles through the heart of the Midwest. Most travelers prefer driving via I-49 South to I-40 East for the most efficient path. The trip typically takes 7 hours depending on traffic near the Memphis metro area. You will pass through scenic parts of Arkansas before crossing the Mississippi River. This route is popular for those seeking a direct connection between the Kansas City suburbs and the blues capital of the South.
Total Distance: 725 km driving distance; 610 km straight-line air distance.
Avoid rush hour traffic in Little Rock by timing your departure before 7 AM.
Spring and Fall offer mild temperatures perfect for driving through the Ozarks.