The drive from Lee's Summit to San Diego, California, is approximately 2,600 kilometers and takes about 25 hours via I-70 W and I-15 S. This route takes you through Kansas, Colorado, Utah, and California. It is a long but straightforward highway drive. Be prepared for heavy traffic as you approach the San Diego metro area.
Total Distance: 2,600 km driving, 2,400 km straight-line.
I-15 can be very busy near San Diego; plan your arrival accordingly.
Spring or Fall for comfortable outdoor sightseeing.