The drive from Lee's Summit to San Francisco, California, is approximately 2,700 kilometers and takes about 26 hours via I-70 W and I-80 W. This route takes you through Kansas, Colorado, Utah, Nevada, and California. It is a long but straightforward highway drive. Be prepared for heavy traffic as you approach the San Francisco metro area.
Total Distance: 2,700 km driving, 2,400 km straight-line.
I-80 can be very busy near San Francisco; plan your arrival accordingly.
Spring or Fall for comfortable outdoor sightseeing.