The journey from Lenexa to Des Moines covers approximately 200 miles. Driving is the most common method, taking about 3 hours via I-35 North. This is a straightforward drive across the state of Kansas, Missouri, and Iowa. There are no direct flights from the Kansas City area to Des Moines that are more practical than driving. This route is well-traveled and offers plenty of stops along the way.
Total Distance: 320 km driving distance; 290 km straight-line air distance.
I-35 is the main highway connecting Kansas City and Des Moines.
Spring or Fall for pleasant weather.