Lewiston
Lewiston
Buffalo
Buffalo
Flight Driving

Lewiston to Buffalo

Updated: 28 May 2026

The trip from Lewiston to Buffalo covers approximately 500 miles. Driving involves taking I-95 South to I-90 West (the New York State Thruway). This route takes you across the entire state of New York, passing through Albany, Syracuse, and Rochester. Alternatively, you can fly from Portland (PWM) to Buffalo Niagara International Airport (BUF). Driving is a straightforward but long journey. Be prepared for tolls on the New York State Thruway.

Total Distance: 800 km driving distance, 680 km straight-line air distance.
Fastest Way
Flying is the fastest, taking about 4 hours including layovers.
Cheapest Way
Driving is the most cost-effective for groups, while bus travel is the cheapest for solo travelers.
Compare Lewiston to Buffalo Routes
Flight
Connecting
Driving
Direct
Duration 4 hours 8 hours 30 mins
Avg Price 200-400 USD 130-180 USD
Operator United/American Personal Vehicle
Route PWM to BUF via a hub like Newark or Philadelphia. I-95 S to I-90 W (New York State Thruway).
Tip Buffalo airport is very close to the city center and Niagara Falls. The Thruway is a toll road; use E-ZPass for convenience.
Travel Tips
  • Driving
    The I-90 is a major highway; watch for speed traps near small towns.
  • Parking
    Buffalo has ample parking; street parking is often free on weekends.
  • Transit
    The NFTA Metro Rail is free for travel within the downtown core.
  • Weather
    Buffalo is known for heavy lake-effect snow; avoid driving during winter storms.
  • Booking
    Book your flight at least 3 weeks in advance for the best rates.
Safety Tips
  • Winter Driving
    If driving in winter, ensure your car is equipped with snow tires and an emergency kit.
  • Vehicle Prep
    Check your fluid levels and tire pressure before starting the long drive.
  • Emergency Kit
    Carry a blanket, flashlight, and water in case of a breakdown on the Thruway.
  • Navigation
    Use a GPS with real-time traffic updates to avoid construction delays on I-90.
People Also Ask
  • Is Buffalo safe?
    Yes, Buffalo is generally safe, especially in the tourist-friendly areas like Canalside.
  • How long is the drive?
    The drive is approximately 8.5 hours depending on traffic and stops.
  • Do I need a car in Buffalo?
    A car is recommended for visiting Niagara Falls and the surrounding suburbs.
  • What is the best way to travel?
    Flying is the fastest, but driving is more flexible for sightseeing.
  • Are there direct trains?
    No, there is no direct train service from Lewiston to Buffalo.
Quick Info
  • From Lewiston, Maine, United States
  • To Buffalo, New York, United States
  • Modes
Best Time to Travel

June to August for pleasant weather and proximity to Niagara Falls.

Things to Do in Buffalo
1
Niagara Falls
Located just 20 minutes from Buffalo, this is one of the world's most famous natural wonders.
2
Buffalo and Erie County Botanical Gardens
Visit this historic glass conservatory featuring exotic plants and beautiful architecture.
3
Albright-Knox Art Gallery
Explore one of the oldest public art institutions in the U.S. with a world-class collection.
4
Canalside
Enjoy the revitalized waterfront area with boat tours, ice skating, and summer concerts.
Tags
Lewiston to Buffalo Maine to NY travel flight to Buffalo driving to Buffalo I-90 route travel tips Maine to Buffalo fastest way to Buffalo cheapest travel Maine