The journey from Lighthouse Point to Key West covers approximately 300 kilometers. The most practical way to travel is by driving south on the Florida Turnpike and then taking the Overseas Highway. You can expect a travel time of 4.5 to 6 hours depending on traffic. Key West is a unique island city at the end of the Florida Keys. Driving is the only realistic option for this scenic trip.
Total Distance: 300 km driving distance; 260 km straight-line air distance.
The Overseas Highway is a scenic route with many bridges.
Winter and spring offer the most pleasant weather for exploring the island.