Littleton
Littleton
Jackson
Jackson
Flight Driving

Littleton to Jackson

Updated: 30 May 2026

The journey from Littleton to Jackson spans approximately 1,300 miles across the Great Plains and the Deep South. Driving via I-70 E and I-55 S is the most common route, taking roughly 20 hours of pure driving time. Alternatively, flying from Denver International Airport (DEN) to Jackson-Medgar Wiley Evers International Airport (JAN) offers a much faster transit. You will traverse diverse landscapes ranging from the Rocky Mountain foothills to the humid Mississippi Delta. This route requires careful planning due to the significant distance and varying weather conditions.

Total Distance: 2,100 km driving, 1,750 km air.
Fastest Way
Flying from DEN to JAN takes approximately 5 hours including layovers.
Cheapest Way
Driving is the cheapest for groups of three or more people.
Compare Littleton to Jackson Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 20 hours
Avg Price $200-$500 $250-$400 in fuel
Operator United Airlines Personal Vehicle
Route DEN to JAN via Houston or Dallas. I-70 E to I-55 S through Kansas and Tennessee.
Tip Book at least three weeks in advance for the best fares. Stop in Memphis for a meal to break up the long drive.
Travel Tips
  • Pack Layers
    Colorado weather changes rapidly, so keep a jacket accessible.
  • Fuel Up
    Fill your tank in major cities to avoid high prices in rural areas.
  • Hydrate
    Drink plenty of water, especially during the high-altitude departure.
  • Check Traffic
    Use navigation apps to avoid construction on I-70.
  • Rest Stops
    Plan for a hotel stay in Memphis if driving solo.
Safety Tips
  • Tire Pressure
    Check your tire pressure before leaving the mountains.
  • Emergency Kit
    Carry a basic roadside emergency kit in your trunk.
  • Weather Alerts
    Monitor local news for severe weather in the Midwest.
  • Night Driving
    Avoid driving through rural areas late at night to reduce wildlife collision risks.
People Also Ask
  • Is there a train to Jackson?
    Amtrak does not provide direct service from Littleton to Jackson.
  • What is the best highway?
    I-70 E and I-55 S are the most efficient routes.
  • Are there direct flights?
    No, all flights from Denver to Jackson require at least one connection.
  • How long is the drive?
    The drive takes approximately 20 hours of active driving time.
  • What is the cost of gas?
    Expect to spend between $250 and $400 depending on vehicle efficiency.
Quick Info
  • From Littleton, Colorado, United States
  • To Jackson, Mississippi, United States
  • Modes
Best Time to Travel

Spring and Fall are ideal to avoid extreme heat in Mississippi and potential snow in Colorado.

Things to Do in Jackson
1
Mississippi Civil Rights Museum
Explore the history of the civil rights movement in Jackson. It features interactive exhibits and powerful storytelling.
2
Denver Botanic Gardens
Visit before you leave Littleton to enjoy world-class plant collections. It is a peaceful start to your journey.
3
Jackson State Capitol
Tour the historic building to see the architecture and learn about state governance. It is located in the heart of downtown.
4
LeFleur's Bluff State Park
Enjoy outdoor activities like fishing and hiking in this urban park. It provides a nice break from city travel.
Tags
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