The trip from Los Angeles to Tampa is a cross-country journey of over 4,000 kilometers. Flying is the most practical method, with direct flights taking about 5 hours. Driving is a massive undertaking, requiring nearly 40 hours of road time via I-10 East. You will cross the entire southern United States, passing through Texas and Louisiana. Flying saves you days of travel time and significant fuel costs.
Total Distance: Driving distance 4,100 km, straight-line air distance 3,500 km.
Look for red-eye flights to arrive in Florida early in the morning.
November to April to avoid the intense summer heat and hurricane season.