No, there is no direct Amtrak service from Lutz to St. Louis.

What is the best highway?

I-75 to I-24 to I-64 is the standard route.

How long is the flight?

Flights take about 5 hours with a connection.

Expect tolls on the Florida Turnpike.

What airport do I use?

Use St. Louis Lambert International (STL).

Lutz

Saint Louis

Flight Driving

Lutz to Saint Louis

Updated: 28 May 2026

The journey from Lutz to St. Louis covers approximately 1,700 kilometers. By car, you will head north on I-75, then transition to I-24 and I-64 to reach the Gateway City. This drive takes about 17 hours of transit time. Flying from Tampa to St. Louis Lambert International Airport is a convenient 5-hour trip with one connection. You will move from the coastal environment of Florida to the historic riverfront city of St. Louis, known for its iconic Gateway Arch.

Total Distance: 1,700 km driving distance; 1,450 km straight-line air distance.

Fastest Way

Flying is the fastest, taking 5 hours total.

Cheapest Way

Driving is the most cost-effective for multiple passengers.

Compare Lutz to Saint Louis Routes

	Flight Connecting	Driving Direct
Duration	5 hours	17 hours
Avg Price	$250-$450	$240 in fuel
Operator	Southwest Airlines	Personal Vehicle
Route	TPA to STL via BNA or MDW.	I-75 N to I-24 W to I-64 W.
Tip	Southwest offers flexible booking options for this route.	Nashville is a great midpoint for a rest stop.

Travel Tips

Traffic
Avoid Nashville during peak rush hours to save time.
Weather
St. Louis can be humid in summer; pack light clothing.
Parking
Use the parking garages near the Arch for easy access to the riverfront.
Dining
Try St. Louis-style pizza and toasted ravioli.
Navigation
Use a GPS to navigate the city's highway system.