The journey from Macedonia to Jacksonville is a significant 900-mile trip. You will typically head south through West Virginia and the Carolinas using I-77 and I-95. Expect a driving time of approximately 14 hours, making it a two-day trip for most travelers. This route takes you through the Appalachian Mountains and down the Atlantic coast. It is a popular path for those heading to Florida for a vacation.
Total Distance: 1,450 km driving distance; 1,200 km straight-line air distance.
Plan an overnight stop in Charlotte or Columbia to break up the drive.
March to May or October to November for pleasant coastal weather.