Yes, it is approximately 11 hours of driving time.

What is the best route?

Taking I-71 to I-65 and then I-40 is the standard route.

Yes, but they require connections from Cleveland Hopkins Airport.

Like any major city, stay in well-lit, populated tourist areas.

What is the best time to visit?

Spring and fall offer the best weather for walking tours.

Macedonia

Memphis

Driving

Macedonia to Memphis

Updated: 28 May 2026

The trip from Macedonia to Memphis is a long-haul journey of approximately 700 miles. You will travel south through Ohio and Kentucky before heading west across Tennessee on I-40. Expect a total driving time of about 11 hours, excluding stops. This route takes you through major cities like Cincinnati and Nashville, providing plenty of options for rest and dining. It is a significant cross-country drive that requires careful planning and vehicle preparation.

Total Distance: 1,130 km driving distance; 950 km straight-line air distance.

Fastest Way

Driving via I-71 and I-40 is the fastest method, taking 11 hours.

Cheapest Way

Driving is the most cost-effective way to transport multiple people to Memphis.

Compare Macedonia to Memphis Routes

Driving

Direct

Duration

11 hours

Avg Price

130-180 USD in fuel

Operator

Personal Vehicle

Route

I-71 S to I-65 S to I-40 W

Break the trip into two days if you prefer to avoid fatigue.

Travel Tips

BBQ Stops
Memphis is famous for its dry-rub ribs; make sure to visit a local institution.
Traffic
Avoid the Nashville I-40/I-65 interchange during morning and evening rush hours.
Accommodation
Stay near downtown for easy access to the main tourist attractions.
Hydration
Keep plenty of water in the car for the long stretch across Tennessee.
Planning
Use a navigation app to monitor for construction delays on I-40.

Safety Tips

Fatigue Management
Switch drivers every 3-4 hours to stay alert on the long highway stretches.
Vehicle Maintenance
Check your oil and coolant levels before embarking on this 700-mile trip.
Night Driving
Avoid driving late at night in rural Tennessee to minimize risk of wildlife collisions.
Emergency Supplies
Carry a spare tire and a jack in good working condition.