Macedonia
Macedonia
Syracuse
Syracuse
Flight Driving

Macedonia to Syracuse

Updated: 28 May 2026

The distance from Macedonia to Syracuse is approximately 350 miles. Flying from Cleveland Hopkins (CLE) to Syracuse Hancock International (SYR) is the most practical choice. Driving takes about 5.5 hours via I-90 East. You will cross the heart of the country and the Northeast. Syracuse is a hub for history and culture.

Total Distance: Driving distance 550 km; straight-line air distance 450 km.
Fastest Way
Connecting flight from CLE to SYR takes about 3 hours total.
Cheapest Way
Driving is significantly cheaper than flying for a group.
Compare Macedonia to Syracuse Routes
Flight
Connecting
Driving
Direct
Duration 3 hours 5.5 hours
Avg Price $140 - $350 $80 - $150 in fuel
Operator American Airlines Personal Vehicle
Route CLE to SYR I-90 E
Tip Book well in advance for the best fares. This is a very manageable drive.
Travel Tips
  • Airport Access
    SYR is connected to the city by public transit.
  • Transportation
    Syracuse is very walkable and has excellent public transit.
  • Weather
    Weather is generally mild and sunny.
  • Dining
    Syracuse has an incredible food scene; try the local cuisine.
  • Traffic
    Avoid the freeways during morning and evening rush hours.
Safety Tips
  • Personal Safety
    Stay in well-lit, populated areas.
  • Driving
    Syracuse traffic can be heavy; use navigation apps.
  • Emergency
    Keep emergency contacts saved in your phone.
  • Public Transit
    Keep your belongings secure on public transit.
People Also Ask
  • Is Syracuse walkable?
    Yes, downtown is very walkable.
  • How long is the flight?
    Connecting flights are about 3 hours.
  • Do I need a car?
    No, public transit is excellent.
  • What is the best time to visit?
    Spring and Fall are the most comfortable.
  • Is it safe?
    Yes, standard urban safety precautions apply.
Quick Info
  • From Macedonia, Ohio, United States
  • To Syracuse, New York, United States
  • Modes
Best Time to Travel

Spring and Fall for pleasant weather.

Things to Do in Syracuse
1
Erie Canal Museum
Features an extensive collection of history from the Erie Canal.
2
Milton J. Rubenstein Museum of Science and Technology
Features interactive exhibits for children.
3
Onondaga Lake Park
Features a lake, gardens, and walking trails.
4
Syracuse University
A historic university with beautiful architecture.
Tags
Macedonia to Syracuse flights to SYR from Cleveland driving to Syracuse from Ohio I-90 route cheapest flights to SYR Ohio to New York road trip traveling to Syracuse Macedonia travel guide