The drive from Mackinaw City to Detroit is a 290-mile journey along the I-75 highway. This route takes you through the heart of the Lower Peninsula, passing through cities like Saginaw and Flint. The drive takes approximately 4.5 hours. It is the primary artery connecting northern Michigan to the Detroit metro area.
Total Distance: 467 km driving.
I-75 is a major interstate with many services.
Anytime, but avoid rush hour in Detroit.