The drive from Mackinaw City to Kalamazoo is a 260-mile journey using I-75 and US-131. This route takes you through the heart of the Lower Peninsula. The drive takes approximately 4 hours. It is the primary artery connecting northern Michigan to the Kalamazoo area.
Total Distance: 418 km driving.
US-131 is a major highway with good speed limits.
Anytime, but autumn is beautiful with the fall colors.