The drive from Mackinaw City to Midland is a 160-mile journey using I-75 and US-10. This route takes you through the heart of the Lower Peninsula. The drive takes approximately 2.5 hours. It is the primary artery connecting northern Michigan to the Midland area.
Total Distance: 257 km driving.
US-10 is a major highway with good speed limits.
Anytime, but avoid rush hour in Midland.