The drive from Madison to Orlando covers 280 kilometers through Central Florida. You will take I-10 East to I-75 South, then connect to the Florida Turnpike. The journey takes approximately 3 hours. This route is very efficient and connects North Florida to the major tourist hub of Orlando.
Total Distance: 280 km driving distance; 250 km straight-line air distance.
The Florida Turnpike involves tolls; use a SunPass for convenience.
Spring or autumn for the most pleasant weather.