The drive from Marble Falls to Amarillo is a 450-mile journey heading north. You will take US-281 North to US-287 North, which will take you across the plains of North Texas and into the Panhandle. This is a long drive, typically taking about 7 hours. Amarillo is known for its proximity to Palo Duro Canyon, the Cadillac Ranch, and its rich ranching history.
Total Distance: 720 km driving distance; 600 km straight-line air distance.
Plan for multiple fuel stops; services are sparse in the Panhandle.
Spring or Fall, to avoid the extreme summer heat and winter cold.