The drive from Mechanicsburg to Erie is approximately 420 kilometers via I-80 and I-79. This route takes you across the northern part of Pennsylvania. The journey typically takes about 4.5 hours. There is no direct passenger rail service. It is a long but scenic drive across the state.
Total Distance: 420 km driving, 350 km air distance.
I-80 is a major trucking route; expect heavy traffic.
Summer for visiting Presque Isle State Park.