Medford
Medford
Baltimore
Baltimore
Train Driving

Medford to Baltimore

Updated: 28 May 2026

The journey from Medford to Baltimore covers approximately 400 miles along the busy Northeast Corridor. You can take the MBTA Orange Line to Boston South Station and board an Amtrak Northeast Regional train for a seamless ride. Alternatively, driving involves navigating the I-95 South through Connecticut, New York, and New Jersey. Traffic near New York City and Philadelphia is notoriously heavy, so plan your departure accordingly. The train offers a more relaxing experience with Wi-Fi and power outlets, bypassing the stress of urban congestion.

Total Distance: Driving distance 645 km, straight-line air distance 580 km.
Fastest Way
Amtrak Acela train, which takes approximately 6 hours and 30 minutes.
Cheapest Way
Bus travel via Greyhound or Peter Pan from South Station, often starting at $50.
Compare Medford to Baltimore Routes
Train
Direct
Driving
Direct
Duration 7 hours 8 hours
Avg Price $80 - $180 $60 - $90 (fuel + tolls)
Operator Amtrak Personal Vehicle
Route South Station to Baltimore Penn Station via Northeast Corridor. I-93 S to I-95 S through CT, NY, NJ, DE, and MD.
Tip Book at least two weeks in advance to secure the lowest fare buckets. Use the E-ZPass transponder to save time and money on the numerous toll bridges and tunnels.
Travel Tips
  • Avoid Rush Hour
    Try to pass through New York City and Philadelphia between 10 AM and 2 PM to avoid peak traffic.
  • Station Access
    Use the MBTA Orange Line from Wellington Station to reach South Station quickly.
  • Dining
    Try the local blue crab cakes at a traditional crab house in the Canton neighborhood.
  • Connectivity
    Amtrak provides free Wi-Fi, but it can be spotty; download your entertainment beforehand.
  • Parking
    If driving, book parking in Baltimore via apps to avoid high daily garage rates.
Safety Tips
  • Stay Alert
    Keep your belongings secure in crowded transit hubs like South Station.
  • Driving Safety
    I-95 is high-speed; maintain a safe following distance, especially in the New Jersey Turnpike section.
  • Neighborhoods
    Stick to well-lit, populated areas when exploring downtown Baltimore at night.
  • Emergency
    Keep the number for local roadside assistance saved in your phone if driving.
People Also Ask
  • Is it better to drive or take the train?
    The train is generally less stressful due to traffic on I-95.
  • How much is the toll on I-95?
    Expect to pay approximately $30-$40 in tolls one-way depending on the route.
  • Does the train go directly to Baltimore?
    Yes, Amtrak Northeast Regional trains stop at Baltimore Penn Station.
  • What is the best time to leave Medford?
    Departing before 6 AM helps you clear the Boston metro area before heavy traffic.
  • Are there direct flights?
    Yes, flights from Logan Airport to BWI are available but require airport security time.
Quick Info
  • From Medford, Massachusetts, United States
  • To Baltimore, Maryland, United States
  • Modes
Best Time to Travel

May and September offer mild weather and avoid the peak summer humidity of the Mid-Atlantic.

Things to Do in Baltimore
1
Inner Harbor
Explore the historic waterfront featuring the National Aquarium and various maritime museums. It serves as the heart of Baltimore's tourism district.
2
Fort McHenry
Visit the birthplace of the Star-Spangled Banner. This national monument offers deep historical insights into the War of 1812.
3
Fells Point
Walk through this historic neighborhood known for its cobblestone streets and 18th-century buildings. It is packed with local pubs and seafood restaurants.
4
Baltimore Museum of Art
Home to the world's largest collection of works by Henri Matisse. Admission is free to the general public.
Tags
Medford to Baltimore train Amtrak Northeast Regional driving Medford to Baltimore I-95 travel tips Baltimore travel guide Boston to Baltimore transport cheapest way to Baltimore fastest route to Baltimore
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