Yes, the Overseas Highway offers some of the best ocean views in the US.

How many bridges are there?

There are 42 bridges connecting the islands.

Do I need a passport?

No, Key West is part of the United States.

No, there is no train service to Key West.

What is the best time to leave?

Leave before 7:00 AM to avoid traffic in the Upper Keys.

Medley

Key West

Driving

Medley to Key West

Updated: 28 May 2026

Traveling from Medley to Key West is an iconic Florida road trip covering 260 kilometers. You will head south to join US-1, also known as the Overseas Highway, which connects the Florida Keys. The route crosses 42 bridges, including the famous Seven Mile Bridge. Expect a drive time of 4 to 5 hours depending on traffic in the Upper Keys. This journey offers unparalleled views of the Atlantic Ocean and the Gulf of Mexico.

Total Distance: 260 km driving, 230 km air.

Fastest Way

Driving via US-1 is the only practical way, taking about 4.5 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Medley to Key West Routes

Driving

Direct

Duration

4 hours 30 mins

Avg Price

$40-$60 in fuel

Operator

Personal Vehicle

Route

Florida Turnpike to US-1 S

Leave early in the morning to avoid weekend traffic congestion in Key Largo.

Travel Tips

Speed Limits
Strictly follow speed limits in the Keys; police enforcement is very active.
Parking
Parking in Key West is limited and expensive; use public garages.
Sun Protection
The sun is intense; wear high-SPF sunscreen even on cloudy days.
Reservations
Book your accommodation well in advance, especially during peak season.
Hydration
Drink plenty of water to stay hydrated in the tropical climate.

Safety Tips

Bridge Safety
Bridges can be narrow and windy; keep both hands on the wheel.
Wildlife
Watch for Key Deer on the roads, especially at dawn and dusk.
Emergency Services
Medical facilities are limited in the lower Keys; drive carefully.
Storm Prep
Monitor weather reports for potential tropical activity.