The journey from Melbourne to Fort Myers covers approximately 180 miles. You will typically head south on I-95 before cutting across the state via SR-80 or similar connectors to reach I-75 South. The drive takes about 3 hours. This route takes you through the heart of South Florida's agricultural and suburban regions. Fort Myers is a gateway to the beautiful islands of Sanibel and Captiva.
Total Distance: 290 km driving, 240 km air distance.
SR-80 can be busy; watch for agricultural vehicles.
Late winter for pleasant weather and outdoor activities.