Is there a direct train?

No, there is no direct Amtrak service from Midway, GA to St. Louis.

What is the best highway?

I-75 North to I-24 West is the most efficient route.

There are no major toll roads on this specific route.

How long is the flight?

Total travel time including layovers is usually 5 to 7 hours.

Chattanooga, TN is a perfect halfway point for a meal.

Midway

St. Louis

Flight Driving

Midway to St. Louis

Updated: 28 May 2026

The journey from Midway to St. Louis spans approximately 1,450 kilometers by road. You will primarily utilize I-75 North through Atlanta before transitioning to I-24 West toward Nashville. Driving takes roughly 14 to 15 hours depending on traffic near major hubs. Alternatively, you can fly from Savannah/Hilton Head International Airport to St. Louis Lambert International. This route crosses the Appalachian foothills and the Mississippi River basin. Expect varied terrain ranging from coastal plains to the rolling hills of the Midwest.

Total Distance: 1,450 km driving distance; 1,180 km straight-line air distance.

Fastest Way

Flight from SAV via Atlanta is the fastest, taking roughly 5 hours total.

Cheapest Way

Driving is the most cost-effective for groups of two or more.

Compare Midway to St. Louis Routes

	Flight Connecting	Driving Direct
Duration	5 hours 15 mins	14 hours 30 mins
Avg Price	$250-$450	$180-$250 in fuel
Operator	Delta Air Lines	Personal Vehicle
Route	SAV to ATL to STL.	I-95 N to I-16 W to I-75 N to I-24 W to I-64 W.
Tip	Book at least 21 days in advance for the best fares.	Avoid Atlanta during rush hour between 7 AM and 9 AM.

Travel Tips

Traffic Alert
Nashville traffic on I-24 can be heavy; check GPS apps before entering the city.
Airport Parking
Use off-site parking lots near SAV to save on daily rates.
Hydration
Keep water in your vehicle during the long drive through Tennessee.
Time Zones
St. Louis is in the Central Time Zone, one hour behind Midway.
Rest Stops
Plan stops in Chattanooga for a scenic break along the Tennessee River.

Safety Tips

Vehicle Check
Ensure your tires and fluids are serviced before a 1,400 km trip.
Night Driving
Avoid driving through the mountainous sections of I-24 at night if possible.
Emergency Kit
Carry a basic roadside kit including jumper cables and a flashlight.
Weather Awareness
Check for winter storm warnings in the Midwest if traveling between November and March.