How long is the drive?

It takes about 16.5 hours of driving time.

Des Moines is generally safe for travelers.

What is the best route?

I-80 East is the only direct and efficient route.

Millcreek

Des Moines

Driving

Millcreek to Des Moines

Updated: 28 May 2026

The drive from Millcreek to Des Moines is a 1,700-kilometer journey across the heart of the United States. You will follow I-80 East through Wyoming, Nebraska, and into Iowa. Expect a travel time of 16 to 17 hours. This route takes you through the high plains and into the agricultural heartland of the Midwest. It is a major cross-country route with plenty of services.

Total Distance: 1,700 km driving, 1,500 km air distance.

Fastest Way

Driving is the fastest, as flights are limited and often expensive.

Cheapest Way

Driving is the most cost-effective way to reach Des Moines.

Compare Millcreek to Des Moines Routes

Driving

Direct

Duration

16 hours 30 mins

Avg Price

$180 - $250 in fuel

Operator

Personal Vehicle

Route

I-80 E.

Wyoming can have extremely high winds; keep a firm grip on the steering wheel.

Travel Tips

Wyoming Winds
Be prepared for high winds in Wyoming, which can affect vehicle stability.
Fuel
Fill up in major towns like Cheyenne or Omaha.
Weather
Iowa can have severe thunderstorms in the summer; monitor the weather.
Fatigue
The long, straight stretches of I-80 can be hypnotic; take frequent breaks.
Navigation
I-80 is very straightforward, but keep a map for rural detours.

Safety Tips

Winter Driving
I-80 in Wyoming is prone to closures due to snow; check conditions before leaving.
Fatigue
This is a very long drive; plan for an overnight stop.
Emergency Kit
Include a blanket and extra water in your kit.
Communication
Cell service is generally good, but keep a backup map.