The distance from Milton to Burlington is approximately 300 km. The most direct way is driving via I-93 North and I-89 North. Driving takes about 3.5 hours. Public transit is not practical. Burlington is a beautiful city on Lake Champlain.
Total Distance: Driving distance 300 km, straight-line air distance 250 km.
The drive through the mountains is scenic.
Summer and Autumn for the best weather and foliage.