St. Louis, the Gateway to the West, is accessible from Mountain View via flights from San Francisco International Airport (SFO) to St. Louis Lambert International Airport (STL). Rail travel is possible via Amtrak to the St. Louis station. This route takes you from the Pacific coast to the heart of Missouri. Plan for a multi-day trip if taking the train, or a quick flight for efficiency.
Total Distance: Driving distance 3,200 km, straight-line air distance 2,800 km.
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| Duration | 60 hours | 5 hours |
| Avg Price | $350 - $900 | $250 - $600 |
| Operator | Amtrak | Southwest Airlines |
| Route | Caltrain to Emeryville, California Zephyr to Chicago, Lincoln Service to St. Louis. | SFO to STL via hubs like Denver or Chicago. |
| Tip | The Lincoln Service offers a comfortable ride into Missouri. | Book early to secure better rates. |
Spring and Autumn for mild weather.