Yes, there are several bus services from Boston to Chicago.

How long does it take?

It takes about 960 minutes by car.

Yes, there are many tolls on this route.

Yes, it is a safe route, but requires attention in heavy traffic.

What is the best time to drive?

Mid-day is best to avoid any potential commuter congestion.

Nashua

Chicago

Driving

Nashua to Chicago

Updated: 31 May 2026

The journey from Nashua to Chicago is approximately 1,600 kilometers. You will primarily use I-90 West. The drive typically takes about 16 hours. This route takes you through several states in the Northeast and Midwest.

Total Distance: 1,600 km driving distance; 1,400 km straight-line air distance.

Fastest Way

Driving is the fastest method, taking roughly 960 minutes.

Cheapest Way

Driving your own vehicle is the most practical and cheapest way to make this trip.

Compare Nashua to Chicago Routes

Driving

Direct

Duration

16 hours

Avg Price

$200-$250 in fuel

Operator

Personal Vehicle

Route

I-90 West.

I-90 is a major highway; stay alert for traffic changes.

Travel Tips

Traffic
I-90 can be busy; expect heavy traffic during peak hours.
Parking
Parking in Chicago is extremely expensive; use public transit.
Navigation
The route is very simple; stay on I-90 West until you reach Chicago.
Road Conditions
Check for any road work or closures on the various state DOT websites.
Local Transit
The Chicago 'L' is the best way to move around the city.