How long is the drive?

It takes about 3 hours and 30 minutes.

Is I-75 the best route?

Yes, it is the most direct and efficient highway.

The route is generally toll-free.

There is no direct bus service; you would need to use private shuttles.

What is the best time to visit?

Spring and fall offer the best weather.

New Port Richey

Jacksonville

Driving

New Port Richey to Jacksonville

Updated: 28 May 2026

Jacksonville is located about 320 kilometers northeast of New Port Richey. The most efficient route involves taking I-75 North to I-10 East. The drive typically takes 3 hours and 30 minutes. This route takes you through the scenic interior of Florida, passing near Gainesville and Lake City. It is a major interstate journey that is well-maintained and easy to navigate.

Total Distance: 320 km driving, 280 km air distance.

Fastest Way

Driving via I-75 N and I-10 E, taking approximately 3 hours 30 minutes.

Cheapest Way

Driving your own vehicle is the most economical choice.

Compare New Port Richey to Jacksonville Routes

Driving

Direct

Duration

3 hours 30 mins

Avg Price

$40-$55 in fuel

Operator

Personal Vehicle

Route

I-75 N to I-10 E.

I-10 can have heavy traffic near the Jacksonville city center.

Travel Tips

Traffic
Avoid the I-10/I-95 interchange in Jacksonville during rush hour.
Fuel Stops
Lake City is a good halfway point for fuel and food.
Navigation
Use GPS to find the best bridge to cross the St. Johns River.
Sun Protection
The Florida sun is strong; keep sunglasses handy for the long drive.
Rest Stops
Use the official Florida rest areas along I-75 for safe breaks.

Safety Tips

Fatigue
Take breaks every two hours to stay alert on the highway.
Weather
Be prepared for sudden heavy rain, which is common in Florida afternoons.
Emergency
Keep a spare tire and jack in your vehicle.
Road Conditions
Watch for wildlife crossing the road in rural sections of I-10.