North Charleston
North Charleston
Key West
Key West
Flight Driving

North Charleston to Key West

Updated: 28 May 2026

The distance from North Charleston to Key West is approximately 1,200 km. Driving is a scenic journey via I-95 South and then US-1 through the Florida Keys, taking about 13-14 hours. Flying from Charleston International Airport (CHS) to Key West International (EYW) is also available, usually with a connection. Key West is known for its laid-back atmosphere, history, and beautiful sunsets.

Total Distance: Driving distance 1,250 km, straight-line air distance 1,050 km.
Fastest Way
Connecting flight from CHS to EYW, taking about 5-6 hours total.
Cheapest Way
Driving is generally the most cost-effective option for this distance.
Compare North Charleston to Key West Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 13 hours
Avg Price $250 - $600 $160 (fuel)
Operator American Airlines N/A
Route CHS to EYW I-95 S to US-1 S
Tip Connections are typically in Miami or Charlotte. The drive through the Florida Keys is beautiful; take your time.
Travel Tips
  • Weather
    Key West is warm and humid; pack light clothing and sunscreen.
  • Transportation
    A car is not needed in Key West; walking, biking, and ride-share are best.
  • Dining
    Try local specialties like key lime pie and fresh seafood.
  • Airport
    EYW is located on the island, making it easy to reach.
  • Atmosphere
    Key West has a laid-back vibe; relax and enjoy the island life.
Safety Tips
  • Personal Security
    Be aware of your surroundings in tourist areas and keep valuables out of sight.
  • Driving
    If driving, be prepared for slow traffic on the Overseas Highway.
  • Emergency
    Keep a charged phone and emergency kit in your car at all times.
  • Navigation
    Use reliable GPS apps to navigate the island's roads.
People Also Ask
  • Is there a direct flight from Charleston to Key West?
    No, most flights require at least one connection.
  • How long is the drive from Charleston to Key West?
    It is a 13-14 hour drive covering over 1,200 km.
  • What is the best way to get around Key West?
    Walking, biking, and ride-share are the best methods.
  • What is Key West famous for?
    Sunsets, history, laid-back atmosphere, and key lime pie.
  • Is Key West expensive?
    It can be, but there are many budget-friendly options if you plan ahead.
Quick Info
  • From North Charleston, South Carolina, United States
  • To Key West, Florida, United States
  • Modes
Best Time to Travel

March to May for the best weather and fewer crowds.

Things to Do in Key West
1
Duval Street
The heart of Key West, filled with bars, restaurants, shops, and entertainment.
2
Ernest Hemingway Home and Museum
The historic home of the famous author, known for its six-toed cats.
3
Mallory Square
A popular spot for the nightly sunset celebration, featuring street performers and food.
4
Dry Tortugas National Park
A remote national park accessible by ferry or seaplane, known for its historic fort and snorkeling.
Tags
North Charleston to Key West travel driving from SC to Key West Charleston to Key West best way to get to Key West Florida Keys travel guide I-95 and US-1 route flights from CHS to EYW Key West tourism