Is there a direct flight from Charleston to Key West?

No, most flights require at least one connection.

How long is the drive from Charleston to Key West?

It is a 13-14 hour drive covering over 1,200 km.

What is the best way to get around Key West?

Walking, biking, and ride-share are the best methods.

What is Key West famous for?

Sunsets, history, laid-back atmosphere, and key lime pie.

Is Key West expensive?

It can be, but there are many budget-friendly options if you plan ahead.

North Charleston

Key West

Flight Driving

North Charleston to Key West

Updated: 28 May 2026

The distance from North Charleston to Key West is approximately 1,200 km. Driving is a scenic journey via I-95 South and then US-1 through the Florida Keys, taking about 13-14 hours. Flying from Charleston International Airport (CHS) to Key West International (EYW) is also available, usually with a connection. Key West is known for its laid-back atmosphere, history, and beautiful sunsets.

Total Distance: Driving distance 1,250 km, straight-line air distance 1,050 km.

Fastest Way

Connecting flight from CHS to EYW, taking about 5-6 hours total.

Cheapest Way

Driving is generally the most cost-effective option for this distance.

Compare North Charleston to Key West Routes

	Flight Connecting	Driving Direct
Duration	5 hours	13 hours
Avg Price	$250 - $600	$160 (fuel)
Operator	American Airlines	N/A
Route	CHS to EYW	I-95 S to US-1 S
Tip	Connections are typically in Miami or Charlotte.	The drive through the Florida Keys is beautiful; take your time.

Travel Tips

Weather
Key West is warm and humid; pack light clothing and sunscreen.
Transportation
A car is not needed in Key West; walking, biking, and ride-share are best.
Dining
Try local specialties like key lime pie and fresh seafood.
Airport
EYW is located on the island, making it easy to reach.
Atmosphere
Key West has a laid-back vibe; relax and enjoy the island life.

Safety Tips

Personal Security
Be aware of your surroundings in tourist areas and keep valuables out of sight.
Driving
If driving, be prepared for slow traffic on the Overseas Highway.
Emergency
Keep a charged phone and emergency kit in your car at all times.
Navigation
Use reliable GPS apps to navigate the island's roads.