Is there a train to Jacksonville?

Yes, Amtrak's Silver Meteor and Silver Star lines stop in Jacksonville.

How long is the drive?

It takes about 3 hours and 30 minutes.

The route via I-75 and I-10 is generally toll-free.

What is the best time to visit?

Spring and fall are the most pleasant seasons.

Yes, Jacksonville International Airport (JAX) serves the city.

Odessa

Jacksonville

Driving

Odessa to Jacksonville

Updated: 28 May 2026

The drive from Odessa to Jacksonville is approximately 220 miles and takes about 3 hours and 30 minutes. You will head north on I-75 before transitioning to I-10 East. This route takes you through the scenic interior of North Florida. Jacksonville is the largest city by area in the contiguous United States. Expect heavy traffic near the I-95 and I-10 interchange in downtown Jacksonville.

Total Distance: 355 km driving distance and 310 km straight-line air distance.

Fastest Way

Driving via I-75 and I-10 is the fastest method, taking about 3.5 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to reach Jacksonville.

Compare Odessa to Jacksonville Routes

Driving

Direct

Duration

3 hours 20 mins

Avg Price

$35-$50 in fuel

Operator

Personal Vehicle

Route

Take SR 54 to I-75 N, merge onto I-10 E.

I-10 East can be very dark at night; ensure your headlights are working.

Travel Tips

Traffic
Avoid the downtown Jacksonville bridges during the 5 PM rush hour.
Local Transit
The JTA Skyway is a free monorail system in the downtown area.
Dining
Try the local Southern-style cuisine in the historic San Marco neighborhood.
Parking
Use the city-owned parking lots for cheaper rates than private garages.
Events
Check for events at the VyStar Veterans Memorial Arena.