Flight
Driving
O'Fallon to Pittsburgh
Updated: 28 May 2026
The trip from O'Fallon to Pittsburgh covers about 700 miles. Driving via I-70 takes approximately 11 hours. You will travel through the Midwest. Alternatively, you can fly from St. Louis (STL) to Pittsburgh (PIT) in about 1 hour and 45 minutes.
Total Distance: 1,130 km driving distance; 950 km straight-line air distance.
Fastest Way
Flying is the fastest, taking less than 2 hours.
Cheapest Way
Driving is the most cost-effective for groups.
Compare O'Fallon to Pittsburgh Routes
|
Direct
|
Direct
|
|
|---|---|---|
| Duration | 1 hour 45 mins | 11 hours |
| Avg Price | 180-400 USD | 130-180 USD |
| Operator | American Airlines | Personal Vehicle |
| Route | STL to PIT | I-70 E |
| Tip | Book early for the best rates to Pittsburgh. | Expect heavy traffic in Columbus and Pittsburgh. |
Travel Tips
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TrafficPittsburgh traffic can be heavy; plan your travel accordingly.
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WalkingDowntown Pittsburgh is walkable.
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AirportPIT is busy; arrive at least 2 hours before your flight.
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DiningTry a Primanti Bros. sandwich.
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NavigationUse a GPS to navigate the city streets.
Safety Tips
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DrivingStay alert on long stretches of highway.
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WeatherBe prepared for cold winters.
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City SafetyStick to well-lit areas in tourist districts.
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EmergencyKeep a roadside assistance contact handy.
People Also Ask
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How long is the drive?The drive takes about 11 hours.
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Is Pittsburgh walkable?Downtown is, but other areas require transport.
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Are there tolls?Some highways in Pennsylvania have tolls.
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What is the best time to visit?Summer is the best time.
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Is it a safe drive?Yes, the interstate route is safe.
Quick Info
- From O'Fallon, Missouri, United States
- To Pittsburgh, Pennsylvania, United States
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Modes
Best Time to Travel
May to September for the best weather.
Things to Do in Pittsburgh
1
Andy Warhol Museum
Explore the largest museum dedicated to a single artist in the US.
2
Duquesne Incline
Ride this historic funicular for stunning views of the city.
3
Point State Park
Visit the confluence of the three rivers in the heart of the city.
4
Carnegie Museum of Natural History
Explore extensive dinosaur exhibits and more.
Tags
O'Fallon to Pittsburgh
driving to Pennsylvania
I-70 route
flights from STL to PIT
Missouri to Pittsburgh
Pittsburgh travel guide
road trip to Pennsylvania
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