The drive from Opelika to Houston is approximately 600 miles and takes about 10 hours. You will head south to the Gulf Coast and then west along I-10 through Mississippi and Louisiana. This route takes you through major Southern cities like Mobile and Baton Rouge. It is a popular route for those traveling to the Texas coast.
Total Distance: 965 km driving, 850 km air distance.
Traffic in Baton Rouge can be very heavy.
Spring or Fall to avoid the humid summer.