The drive from Orange Beach to Memphis covers 700 kilometers. You will travel north on I-65 and then west on I-22. The journey takes about 7 hours. You will pass through Birmingham and Tupelo. This route is the most efficient way to reach the home of the blues.
Total Distance: 700 km driving distance; 630 km straight-line air distance.
Traffic near Birmingham can be heavy.
Spring and Fall for pleasant weather.