The distance from Orlando to St. Louis is approximately 1,600 kilometers. Flying is the most practical mode of transport, with direct flights from MCO to STL taking about 2 hours 30 mins. Driving would take over 15 hours. St. Louis is famous for the Gateway Arch, its rich jazz history, and delicious barbecue. Upon arrival at St. Louis Lambert International Airport (STL), you can take the MetroLink light rail directly into the city center.
Total Distance: 1,600 km driving distance; 1,500 km straight-line air distance.
Southwest offers frequent direct flights on this route.
April to June or September to October for mild weather.