How long is the drive?

The drive typically takes 8 hours.

What is the best route?

I-35/I-70 is the most direct highway.

No, there are no toll roads on this route.

No, there is no direct passenger rail service between Owatonna and Saint Louis.

Is it a scenic drive?

It is a classic Midwestern drive through rolling farmland.

Owatonna

Saint Louis

Driving

Owatonna to Saint Louis

Updated: 30 May 2026

The drive from Owatonna to Saint Louis is a 500-mile journey heading south on Interstate 35 and east on Interstate 70. You will pass through Des Moines, IA, and Kansas City, MO, before reaching Saint Louis. The route is primarily flat, agricultural land, making for a consistent and relatively easy drive. The total travel time is approximately 8 hours. It is a major north-south and east-west artery connecting the states.

Total Distance: 805 km driving distance; 720 km straight-line air distance.

Fastest Way

Driving via I-35/I-70 is the fastest route, taking about 8 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Owatonna to Saint Louis Routes

Driving

Direct

Duration

8 hours

Avg Price

$90-$100 in fuel

Operator

Personal Vehicle

Route

I-35 South to I-70 East

Be aware of speed limit changes when passing through small towns.

Travel Tips

Speed Traps
Be mindful of speed limits in small towns along I-70; they are strictly enforced.
Rest Stops
There are several well-maintained rest areas along I-35 and I-70.
Weather Prep
Check for wind advisories, as the open plains can experience high crosswinds.
Fueling
Gas prices are often competitive in Kansas City, MO.
Navigation
Use a GPS to navigate the city streets of Saint Louis.

Safety Tips

Fatigue
Take regular breaks to stay alert during the 8-hour drive.
Winter Driving
I-70 can be prone to blowing snow; check road reports before winter travel.
Emergency Kit
Carry a basic emergency kit, as help can be far away on rural stretches.
Visibility
Keep your headlights on during overcast days to remain visible.