The drive from Owensboro to Oklahoma City covers approximately 720 miles. You will travel west through Kentucky, Tennessee, and Arkansas, staying on I-40 W for the majority of the trip. This route takes you directly into the heart of Oklahoma. Expect a drive time of about 11 hours. You will pass through major cities like Memphis and Little Rock.
Total Distance: 1,150 km driving distance; 920 km straight-line air distance.
Plan for heavy traffic in Memphis and Little Rock.
Spring and fall for comfortable temperatures.